Depends where you go, if planning some 3 week remote hiking in ie Nepal it may not be the best approach.
Ie I've recently spent 2 weeks in remote islands in Sulawesi, Indonesia and didn't bring enough mosquito spray. Well, on whole island chain I was in, nobody in tiny local shops ever had one. When asked, they told me they suck up malaria if caught and move on, sort of how we deal with flu. Luckily dengue wasn't there. So suck it up I did, luckily it seems I avoided it (knock on the wood).
With spray comes sunscreen. Some basic diving equipment. Non-tiny first aid kid. Some photography stuff. But yeah for that one I could still put it all into 1 medium backpack, just liquids travelled separately. For that Nepal, backpack was bigger. For Aconcagua, there was an extra big duffel bag. If doing full camping and cooking, one backpack but much bigger.
Ie I've recently spent 2 weeks in remote islands in Sulawesi, Indonesia and didn't bring enough mosquito spray. Well, on whole island chain I was in, nobody in tiny local shops ever had one. When asked, they told me they suck up malaria if caught and move on, sort of how we deal with flu. Luckily dengue wasn't there. So suck it up I did, luckily it seems I avoided it (knock on the wood).
With spray comes sunscreen. Some basic diving equipment. Non-tiny first aid kid. Some photography stuff. But yeah for that one I could still put it all into 1 medium backpack, just liquids travelled separately. For that Nepal, backpack was bigger. For Aconcagua, there was an extra big duffel bag. If doing full camping and cooking, one backpack but much bigger.